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The remainder of the iron is in the heme of cytochromes, iron-sulfur center (ISC)-containing proteins, and in non-heme and non-ISC iron-containing proteins

As mentioned earlier, Nrf2 forms heterodimers with the sMaf proteins and recognizes the AREs in the genome (72)

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PLoS ONE 6 , e19645 (2011)

By limiting the transport of these molecules to the cell membrane, H 2 decreases NADPH oxidase activity, reduces the generation of ROS, and ultimately achieves an antioxidant effect

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