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Allen sent both letters to Congress, and at the same time wrote to that body, urging the justice of the demand of his state

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In this Review, we explore both recently discovered compounds and established envelope-targeting antibiotics, including compounds that target Gram-positive bacteria, more complex Gram-negative bacteria and mycobacterial pathogens, shedding light on this still clinically underexplored and vital therapeutic approach

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Since 2011, four direct-acting antivirals (DAAs) have been FDA-approved for chronic infection caused by HCV genotype 1: boceprevir (Victrelis), telaprevir (Incivek), simeprevir (Olysio), and sofosbuvir (Sovaldi) ( TABLE 2 )