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Warning: It may cause mild dryness or redness at the beginning of use, so it is recommended to start gradually (every other day) until the skin adapts

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The pharmacological profile that makes Melanotan 2 uniquely significant in melanocortin research is its broad multi-receptor activity binding with high affinity to MC1R on peripheral melanocytes driving melanogenesis, MC3R and MC4R in the hypothalamus and limbic system influencing energy homeostasis and motivational circuits, and producing downstream autonomic responses through central MC4R activation

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References Goldstein, I, Kim, NN, Clayton, AH, et al

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Amylin - Its role in the homeostatic and hedonic control of eating and recent developments of amylin analogs to treat obesity

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