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Unlike beta-1 receptors in cardiac tissue or beta-2 receptors in smooth muscle, beta-3 receptors are predominantly expressed in adipose tissue and bladder, with limited cardiovascular effects

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Conclusion: These data do not provide evidence of sex differences in the association between CRP or IL-6 and MACE after ischaemic stroke

The glucagon arm is what distinguishes it from every GLP-1 and dual-agonist compound it increases energy expenditure in addition to the appetite and glycemic effects of the incretin receptors ( Coskun et al., Cell Metab 2022 )
