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Neurodegenerative diseases (NDDs), also known as neurodegenerative diseases, are a class of disorders characterized by the progressive degeneration of neuronal structure or function in the central or peripheral nervous systems (Wilson et al., 2023)

10.3389/fnut.2021.627289 102 RiedelC.-U.FoataF.PhilippeD.AdolfssonO.EikmannsB.-J.BlumS

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Accordingly, pertubrations in NMDAR function are implicated in a wide range of neurological conditions (e.g., epilepsy/seizures, stroke and traumatic brain injury, Alzheimers and Huntingtons disease, neuropathic pain), neuropsychiatric conditions (e.g., depression, schizophrenia, addiction, anxiety), and neurodevelopmental disorders (e.g., autism) [1, 6, 10, 84, 119,120,121,122,123,124]