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The expression of phosphorylated STAT3, JAK1, and JAK2 was also reduced (164), which reduced VEGF secretion and nuclear phosphorylated STAT3 translocation for CoCl2-stimulated HER2+ BT-474 cells ( Figure 2 )

However, constitutive PPAR expression in cardiomyocytes of Ppara / mice did not cause cardiac dysfunction, despite increased myocardial lipid content (11), indicating a toxic role for cardiac PPAR when PPAR is activated as well

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[DOI] [PubMed] [Google Scholar] 98.Global Initiative for Chronic Obstructive Lung Disease