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10.1016/j.cell.2013.05.027 49 ChangY

FOXO4-DRI is currently explored in research focused on cellular aging, tissue rejuvenation, vascular health, and regenerative biology
Research suggests that after the age of 20, our natural levels can decrease by about 1% to 10% per decade

Cognition and type 1 diabetes in children and adolescents
Beneficial effects have likewise been documented with respect to cardiovascular risk factors, including hypertension (430) and dyslipidemia (431, 432)

Mol Cancer Ther 12(11): 2494-2504, 2013