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Researchers and clinicians using it do so based on extrapolation from animal data and accumulating clinical experience rather than proven efficacy in humans

In dermal fibroblasts, GHK-Cu reduces TNF-alpha-induced secretion of IL-6, a major positive regulator of fibrinogen synthesis and inflammatory responses

That means less repair, less energy, and slower recovery

This may be the clue that to regain the tissue integrity after wounding, BPC 157 may accommodate the healing depending on the tissue and injury conditions

doi: 10.3389/fbioe.2021.677576 Received 07 March 2021 Accepted 12 April 2021 Published 29 April 2021 Volume 9 - 2021 Edited by Zhen Li, AO Research Institute, Switzerland Reviewed by Guangli Suo, Suzhou Institute of Nano-tech and Nano-bionics (CAS), China