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Nuclei were stained with DAPI and anti- -H2AX antibody was used to mark double-strand breaks sites

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Chronic demyelination in MS results either from an age-related decline in oligodendrocyte precursor cells (OPCs) or a reduced ability of these cells to differentiate into mature oligodendrocytes (mOL) in the environment of the WM lesions due to the presence of pro-inflammatory cytokines and myelin inhibitory proteins (57, 58)

There is benefit in the inferior caval vein occlusion (Vukojevic et al., 2018

Potential for Combining Antioxidants with Emerging Therapies : Antioxidants may enhance the efficacy of several treatment modalities, including immunotherapy, photodynamic therapy, gene therapy, and synergistic combinations