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[Please see additional research results in the attachment] Use: For mixing in any cosmetic formulations Mixing method: Mix in water, avoid heat and pH should be between 3-6

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Missing values were filled using the softwares Fill Gap feature (mass tolerance 5 ppm, S/N tolerance 1.5)

Nephroprotective effects of hesperidin on ifosfamide-induced acute nephrotoxicity in rats: role of nf-b/tnf-/il-1, P53/caspase-3/bax/bcl-2, and atf6/ire1/perk/grp78 signaling pathways

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For dietary PAH exposure, the calculation follows: Where: C = contaminant concentration (g/kg food) IR = ingestion rate (kg food/day) EF = exposure frequency (days/year) ED = exposure duration (years) CSF = cancer slope factor (mg/kg-day) 1 BW = body weight (kg) AT = averaging time (days over lifetime) Regulatory agencies typically consider ILCR values 10 4 as unacceptable, requiring remediation