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Als2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth

It helps avoid serious problems linked to B12 deficiency

The volume per unit stays the same
In fact the ADAGIO-study has given profound evidence for a disease-modifying effect of 1 mg/day rasagiline, while there was not such benefit at a 2 mg/day dosis (Table 4)

Many providers set a minimum weight, commonly around 100 pounds, in addition to an age minimum, because fluid and nutrient dosing is calculated based on body mass
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