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2013 May;136(Pt 5):1476-87

A 2 mg target dose is 2,000 mcg

Talk with your healthcare practitioner about any concerns regarding your medications

Patients with scoliosis should be closely monitored as there's a risk of scoliosis progression

First-pass metabolism occurs when a compound is absorbed from the gut and passes through the liver, where it can be partially broken down before reaching the rest of the body

Disruption of AP1S1, causing a novel neurocutaneous syndrome, perturbs development of the skin and spinal cord
