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research shows no additional benefit above 1 mg daily Important: Doses above 1 mg (1,000 mcg) daily showed no additional metabolic benefits in clinical research
On the other hand, B12 helps produce blood cells and fights tiredness caused by a deficiency

TRAP is a osteoclast specific marker that directly reflects bone resorption activity

Fabrication of a three-dimensional nanostructured biomaterial for tissue engineering of bone

Pharmaceutical Research 2010

It can also help prevent cell apoptosis which helps maintain cell viability and contribute to overall mitochondrial function