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The 16S rRNA gene sequencing and phylum analysis revealed an increased relative abundance of Verrucomicrobia and drastic change in the ratio of Bacteroidetes and Firmicutes (Shen et al., 2017)

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The quantification of F4/80 + macrophages revealed less macrophage infiltration in cyanidin supplemented Sgca mice

In research models, this mechanism has been studied in the context of photoprotection in UV-sensitive conditions particularly erythropoietic protoporphyria (EPP), where clinical development of afamelanotide as a subcutaneous implant has resulted in regulatory approval in Europe and the United States