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This review will summarize receptor-related mechanisms that could underlie tolerance especially receptor desensitization

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Therefore, these confounders must be strictly controlled during study so that the results across samples and studies can be comparable

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In the medical community, there is also an increased feeling that we may not be using these powerful drugs most healthily, and new protocols are emerging

NE levels also increase in patients with Pseudomonas aeruginosa infection and during exacerbations, and decrease with the use of antibiotic treatment.1618 To date, NE is the biomarker that has shown best results for the assessment of bronchiectasis patients