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p=0.007), the primary endpoint, and slowed unconfirmed 1.5-point EDSS progression (-28%

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doi:10.1345/aph.1K559

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Discussion To guide further applications and studies of crown ether-based (pseudo)rotaxane systems, we summarize the factors influencing dethreading as follows: (i) Benzo-fused substitution on the macrocycle has the most significant impact on the dethreading rate

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