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BMC Pediatr 2015;15:218 10.1186/s12887-015-0533-2 [DOI] [PMC free article] [PubMed] [Google Scholar] 16

The documented research protocol is once-daily dosing in the activation phase (roughly weeks 1-4), then the same per-dose amount at a reduced 3-5x/week frequency in maintenance

However, you should go to a hospital or seek medical attention immediately if you experience symptoms of a severe allergic reaction, like rash, itching, or swelling (especially of the face, tongue/, or throat), severe dizziness, or trouble breathing

They also meet validated manufacturing standards such as Good Manufacturing Practice (GMP)

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