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GSTs also play an important role in tetrapyrrole metabolism because GSTs can bind different porphyrins such as protoporphyrin ix, mesoporphyrin, coproporphyrin, Mg protoporphyrin, and uroporphyrin

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The small molecule fraction of FBS (smFBS) prepared by filtering FBS through a size-exclusion membrane also failed to mimic the death-inducing activity of FBS
