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Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

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doi:10.1016/j.amepre.2018.04.042 Makarem N, Castro-Diehl C, St-Onge MP, et al

Histology showed features of LSc and melanophages in the papillary dermis, and a diagnosis of PIH was made