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Roles of Raf/MEK/ERK and PI3K/Akt/mTOR pathways in prevention of apoptosis and induction of drug resistance in myeloid hematopoietic cells

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High levels of glutathione (GSH) are observed in the majority of tumors, contributing to cancer progression and treatment resistance in part by preventing glutathione peroxidase 4dependent (GPX4-dependent) ferroptosis

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MM, HM, SWA, LA and DZ performed experiments

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After centrifugation, the protein concentration in the supernatant was determined

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Wiener-Megnazi Z, Auslender R, Dirnfeld M (2012) Advanced paternal age and reproductive outcome

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