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These patients experienced a lack of remission or early relapse at 24 months after diagnosis

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AIP in particular presents an attractive opportunity for liver-targeted gene therapy because only a few functional hepatocytes expressing HMBS are needed to metabolize ALA/PBG in order to avert acute attacks

Dermatologists are in a unique position to identify inappropriate use of supplements based on cutaneous manifestations and must educate patients and encourage informed decision

At this time, the bodys demand for thyroid hormones increases, and the small amount of iodine stored in the gland is consumed more quickly without being replaced, resulting in a more rapid loss of thyroid status