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Methylcobalamin can cross the blood-brain barrier (BBB) without the needed conversion
In future trials it will be important to keep track of comorbidities for clinical trial design, either for the purpose of post hoc subgroup analysis or a priori subgroup recruitment, since the neuroathophysiological mechanisms in IC/ BPS patients with different co-morbidities are likely to be different
And like fibromyalgia, women are much more likely to have CFS than men
Wixler, V., Zaytsev, I
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