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Acevaltrate as a novel ferroptosis inducer with dual targets of PCBP1/2 and GPX4 in colorectal cancer

The antisense strand of the siRNA is incorporated into the RISC complex, while the sense strand of the siRNA duplex is lost due to helicase activity [108]

One-carbon metabolism The so-called one-carbon metabolism cycles carbon units from different amino acids, generating several different outputs and integrating several cellular nutrient statuses (Figure 2)

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