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Environmental toxicants such as bisphenol A (BPA) and nickel also induce ROS-mediated ER stress, further disrupting reproductive homeostasis [132,133,134]

Microbiome changes are gradual

Isotretinoin purchased from MedChemExpress

Now, I know this is super nerdy but hang with me here because I promise it is worth it

Wang et al., 2007)

The superoxide anion (O 2 ), hydroxyl radical ( HO), and hydrogen peroxide (H 2 O 2 ) are the three most physiologically significant ROS (Table 3) (Phaniendra et al ., 2015)
