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378 Furthermore, the ArtemiC oral spray (artemisinin 6 mg/mL, curcumin 20 mg/mL, frankincense 15 mg/mL, and vitamin C 60 mg/mL) given twice a day on day 1 and 2 of a double-blind multicenter phase II clinical trial showed remarkable clinical improvement, including reduced O 2 supplementation duration, fever duration, hospital admission time, and abnormal oxygen saturation (SpO 2 ) duration in patients with COVID-19 ( n = 33), compared to those who received a placebo ( n = 17)

It can be absorbed from the diet or synthesized by the human body from oleic acid 5

Additionally, there is a risk of peptide-related impurities and API characterization as the drug is not regulated by the FDA

Another method for screening and selecting enzymes with new properties using CFE is to compartmentalize reactions to link genotype and phenotype