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Factors such as the medication type, dosage, and individual genetic variations can influence these changes

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Enhanced migration is driven by CD44 overexpression and ECM accumulation [39]

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TP53 loss results in downregulation of mitochondrial respiration and oxidative metabolism, which contribute to the Warburg effect in tumor cells, thus linking to tumor progression (166)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Chaowattanapanit, S., Silpa-Archa, N., Kohli, I., Lim, H

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GH-deficient subjects required a dose of approximately 60 ?g/kg/d, whereas those with idiopathic short stature required more than 120 ?g/kg/d, which exceeds the labeled dose and would not be reasonable to use in a standard clinical care of a pediatric patient

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2c), they lived longer (Fig

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