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Clin Transl Immunol (2021) 10:e1338

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7 Clinical evidences supporting the anti-fibrotic effects of curcumin In patients with non-alcoholic fatty liver disease (NAFLD), a randomized controlled trial (RCT) found that 12 weeks of curcumin supplementation (1,500 mg/day) significantly reduced hepatic fibrosis scores compared to baseline, although it was not superior to lifestyle modification alone in ameliorating systemic inflammation (Saadati et al., 2019)

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