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The pore-forming -toxin from clostridium septicum activates the MAPK pathway in a Ras-c-Raf-dependent and independent manner

Feno and VPA + Feno groups were treated with Feno (50 mg/kg dissolved in 0.5% sodium carboxymethylcellulose (CMC-Na)) for 28 days

Result showed that children on exclusion diets were associated with distinct microbial and metabolic profile at baseline, and that B-GOS improved social behavior only in children already following the exclusion diet, while also inducing specific shift in gut microbiota and metabolites