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CrossRef Unlocking the potential of Polygonatum odoratum protein hydrolysate: identification, characterization, and antidiabetic activity in HFD/STZ-induced type 2 diabetic mice Yuying Ge, Yangqiannan Tang, Yuai Lu, Shiyi Hou, Zihao Dai, Ruiyao Xiong, Shuang Chen, Yamei Li, Bohou Xia Frontiers in Nutrition.2026;[Epub] CrossRef Association of environmental chemical exposure with metabolic dysfunction-associated steatotic liver disease: a cross-sectional and network toxicology analysis Guodong Yang, Wenli He, Xin Qiu, Shuang Shen, Yifei Feng, Yi Peng, Taixin Yang, Zhaochan Wen, Peishu Li, Huili Luo, Xinyuan Wu, Ze Su, Bangde Xiang European Journal of Medical Research.2026;[Epub] CrossRef Reprogramming of fatty acid metabolism induced by environmental pollutant exposure and its role in the toxic effects of environmental pollutants Xuyi Liu, Guozhu Ye, Qiansheng Huang Environmental Geochemistry and Health.2026;[Epub] CrossRef The HepG2 Cell Line as a Model for Studying Metabolic Dysfunction-Associated Steatotic Liver Disease Anna Kotlyarova, Aleksandra Iskrina, Stanislav Kotlyarov International Journal of Molecular Sciences.2026

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Also, family history revealed this mutation was found earlier in two distant cousins, genetically linked through the patients grandmother ( figure 1 )

Validation of the expression of target genes We selected four target genes ( PIK3R1 , HIF-1A , MAPK1 , and TLR-4 ) to verify the integrated analysis results