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Down-regulation of SelF in cancer cell lines leads to up-regulation of p21 and p27 (cell cycle inhibitors) and subsequently induces a slowdown in cellular proliferation and triggers a state of growth arrest specifically in colon and liver cancer cells (205207)

[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Fushimi H., Inoue T., Yamada Y., Horie H., Kameyama M., Inoue K., Minami T., Okazaki Y
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doi: 10.1007/112_2020_51 63 DixonSJOlzmannJA

Side effects from IV glutathione can include nausea, allergic reactions, nerve damage, kidney stress, and in rare cases, liver abnormalities

Defensin-release by PVL-treated neutrophils, as well as oxidative reactions detected by an antibody directed against the acrolein derived adduct N -(3-formyl-3,4-dehydropiperidino)-lysine (FDP-lysine) (see below), were also visualised by fluorescence microscopy (Supplementary Fig
