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Ergothioneine supplementation attenuated diabetes-related alterations in sirtuin-1 and NF- B mRNA expression in the liver, as well as the sterol regulatory element-binding transcription factor 1 and fatty acid synthase, the rate-limiting enzyme in fatty acid synthesis (91)

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Due to the small number of adolescents in this latter category, the underweight and NW categories were combined

The amplicons were sequenced using the IonS5 XL platform, and gene library construction, sequencing, and data analysis were performed by Novogene Bioinformatics (Tianjin, China)

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The major pathological processes contributing to kidney dysfunction include apoptosis, oxidative stress, fibrosis, and inflammation