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In another study, tumor suppressor- Na + /H + exchanger regulatory factor 1 (NHERF1/EBP50), an adaptor molecule known to suppress Wnt signaling has been observed to be downregulated in colon cancer cells and is associated with decreased survival and increased intestinal tumor burden ( NHERF1 promoter in colon cancer ( Histone Modifications The Wnt pathway employs diverse factors to regulate target gene expression and converges with epigenetic signaling at Wnt response elements through recruitment of epigenetic modulators

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The Y-Maze for Assessment of Spatial Working and Reference Memory in Mice. Methods in molecular biology (Clifton, N.J.) vol