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Likewise, Bax upregulation can be transient or reflect selective apoptosis of irreversibly damaged cells during tissue remodeling, rather than widespread apoptotic injury 53

Whereas -carotene is a source of two moles of retinaldehyde (and thus two moles of retinol), -carotene and -cryptoxanthin provide only a single mole each of retinol

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Rapid translocation of Zn(2+) from presynaptic terminals into postsynaptic hippocampal neurons after physiological stimulation

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in the other outcome, the injured tissue continues to deteriorate, and the mechanism of the persisting damage involves gliosis with the loss of support of neurotrophic factors, persistent inflammatory receptor activation, and changes in microglia and astrocytes that continue to release harmful cytokines, which promote neuronal death and axonal injury