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There are many evidence-based ways to help a dog heal from an injury or manage arthritis that are far safer than experimental peptides, says Dr

Reviews note the need for larger animal studies and more detailed mechanistic investigations [11]

Although the mechanisms by which these reagents modulate GPx1 expression are not clear, it has been shown that GPx1 can be upregulated by activation of the peroxisome proliferator-activated receptor--coactivator-1a (PGC1) pathway, possibly via the subsequent activation of Nrf2 [161]

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doi: 10.1016/j.lfs.2006.09.018

Endocr Connect (2017) 6(4):R52R8