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Due to the key regulatory role of NF-B signaling in immune and inflammatory responses, its dysregulation has been strongly associated with a variety of human diseases, including cancer, inflammatory diseases, autoimmune disorders, viral infections, and infectious shock

TGF- signaling-related genes and thoracic aortic aneurysms and dissections

Repression of peroxisome proliferation-activated receptor coactivator-1 by p53 after kidney injury promotes mitochondrial damage and maladaptive kidney repair

Given that the sentinel lymph nodes or TDLNs are often surgically removed during the processes of cancer diagnosis and treatment, a better understanding of the roles of TDLNs and the tumor-draining lymphosomes in cancer vaccination and radioimmunotherapy is needed to enhance treatment efficacy