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We demonstrate that 15% calorie restriction initiated at 4 months of age improves both metabolic and physical function at 6 and 17 months of age in WT littermates but fails to improve healthspan in Gcgr KO mice

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This bipartite strategy of anti-immunology aims at colonization of the erythrocytic niche, where the bacteria are protected from both the innate and adaptive immunity and persist in a compartment competent for vector transmission. Intruders below the Radar: Molecular Pathogenesis of Bartonella spp

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doi: 10.1371/journal.pone.0261259, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 82.Thiele JJ, Ekanayake-Mudiyanselage S