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It was documented that dietary supplementation containing vit B12 and folate, in a model of ischemic injury in mice, could improve the motor activity in the rotarod test (68)

Lower NAD levels have been associated with fatigue, brain fog, slower recovery, decreased metabolic efficiency, increased oxidative stress, and reduced cellular repair

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Mercola Methyl B12 Energy Boost Spray Pros 1000 mcg methylcobalamin per dose Convenient spray for fast absorption Supports energy, mood, and metabolism Cons Must be used daily Flavor may not suit all May not suit those sensitive to spray mechanisms Form: Spray | Dosage: 4 sprays daily | Servings per container: 39 | Price: $16.97 | Third-party tested: Yes Description: Dr

They cited Pyo et al