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Instead, carnitine assists the transport and metabolism of fatty acids into mitochondria, and in so doing, carnitine maintains a balance between free and esterified CoA, as an excess of acyl-CoA intermediates is potentially toxic to cells

With regard to gender, there was a significant negative correlation between estrogen level and serum free carnitine in females (58)

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A typical starting dose is between 0.25 mg to 0.5 mg injected once daily, usually in the evening