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This demonstrates that the use of mesoporous silica NPs for the treatment of CNS diseases does not cause serious side effects

Funding Statement This study was funded by Novartis Pharma AG, Basel, Switzerland

Although it is a derivative of hGH, it does not act via the GH receptor (GHR)

Clinical studies indicate that rosuvastatin reduces urinary IL-6 and CD40 ligand levels in patients with DKD, correlating with a reduction in macrophage density in renal biopsies (123)

The injections are given intramuscularly

If successful, CAQK could serve as a delivery vehicle for other therapeutic peptides, concentrating their effects exactly where damage has occurred