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To interrogate this, we have developed a series of in vivo models to induce Gclc deletion in adult animals

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Regardless of differences in study designs and diagnostic criteria, all the studies have reported significant reductions of HIT-associated symptoms as a result of DAO supplementation

42 Since inflammation and histamine are underlying contributors to rosacea, PEA has potential therapeutic value in this condition

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Concomitantly, selective degeneration of nigrostriatal dopaminergic neurons results in severe dopamine depletion within the basal ganglia circuitry [12, 13]