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Vitamin B12 and Methylfolate (5-MTHF) Vitamin B12 works in the methylation cycle together with methylfolate (5-MTHF)

It is essential for the production of myelin, a protective layer around nerves that helps transmit signals efficiently in the brain

Supplementation may involve various forms of cobalamin: adenosylcobalamin, cyanocobalamin, methylcobalamin, or hydroxocobalamin

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The finding that maternal supplementation during pregnancy and lactation significantly increased vitamin B-12 concentrations in breast milk is novel and potentially important

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