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Together, our data demonstrate that caspase-3-mediated cleavage of XKR8 triggers lipid scrambling, resulting in widespread phospholipids reorganization across the bilayers of PM during NET formation

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Hence, an interspecies comparison of cysteine reactivity is not trivial, since both sites, Cys78 and 87, might compete for binding reactions

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In parallel, cagrilintide influences glucose homeostasis research models through mechanisms that include modulation of glucagon secretion from pancreatic alpha cells and regulation of gastric emptying rate, the latter of which affects postprandial glucose flux into the circulation