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D.et al (2025)

Common causes include contaminated vial stoppers (not swabbed with alcohol before drawing), exposure to temperature extremes, or inadvertent shaking

Indirect markers include elevated oxidative stress markers, poor recovery from exercise, chronic fatigue, weakened immune function, or elevated liver enzymes

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Patients who I recommend be screened for MTHFR mutations: Mood disorders: depression, anxiety, irritability, mood swings, bipolar Infants and children of parents with MTHFR mutations Family members related to someone with MTHFR mutations Infertility and Pre-conception care: test both man and woman Elevated folate (not processing to active 5-MTHF due to inability to methylate) Elevated homocysteine (due to low active 5-MTHF and methylcobalamin) Elevated s-adenosylhomocysteine (due to low active 5-MTHF and methylcobalamin) Elevated serum cobalamin (due to inability to methylate cyanocobalamin to methylcobalamin) Elevated methylmalonic acid (due to methylcobalamin deficiency) Patients with syndromes: IBS, multiple chemical sensitivity, fibromyalgia, Down syndrome, chronic fatigue syndrome Neurological disorders: Multiple sclerosis, Autism, Alzheimers, Epilepsy, Parkinson's Cancer: family history of cancer or undergoing cancer treatment Cervical dysplasia Cardiovascular risk: family history of strokes, embolisms, heart attacks, clots, hypertension Birth defects: cleft palate, tetralogy of Fallot, spinal bifida, midline defects Drug sensitivities: methotrexate, anti-seizure meds, nitrous oxide, anesthesia If you are interested in knowing more about your genes, the 23andme gene test will be the best $99 investment you've ever spent

IV therapy allows for large quantities of natural substances for immunity which often give gastrointestinal distress if taken orally