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In summary, rational design has led to the development of two long-acting GLP-1 analogs, liraglutide and semaglutide, that have made a vast contribution to the management of T2D in terms of improvements in glycemic control, body weight, blood pressure, lipids, beta-cell function, and CV outcomes

[DOI] [PMC free article] [PubMed] [Google Scholar] Wijesekara T

Many people experience mild gastrointestinal symptoms during dose escalation, which often improve as the body adjusts to treatment

His research produced a remarkable body of evidence, including clinical trials spanning 6-12 years with hundreds of participants documenting reduced mortality and improved organ function

B12 is a water-soluble vitamin, and when administered under medical supervision, its a safe and effective way to improve energy and support metabolism

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