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Moreover, altered plasma A40/A42 ratios and tau phosphorylation levels are critical biomarkers associated with AD progression, with elevated ratios correlating positively with increased cognitive impairment severity (Scholl et al., 2024

(2018) 13:e0195279

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This M1 reprogramming decreases the immune-tolerant environment within tumors, reducing tumor progression and potentially enhancing the efficacy of immunotherapies

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APOE and Alzheimers disease: neuroimaging of metabolic and cerebrovascular dysfunction