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Thus, targeting the PPP for cancer therapy may be challenging (BOX2)
Enough protein to support normal metabolic processes

However, the six studies showed a high heterogeneity (MD 2.70, 95% CI 2.04 to 7.44
Dysregulated IGF signaling seems to be a contributing factor
[DOI] [PMC free article] [PubMed] [Google Scholar] 228.Xu K., Yu L., Wang Z., Lin P., Zhang N., Xing Y., Yang N

GHS-R1a, also known as ghrelin receptor, is a G protein-coupled receptor (GPCR) widely distributed on the hypothalamus and pituitary gland where it exerts its major functions of regulating appetite and growth hormone (GH) secretion
