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Macropinocytosis is a non-selective, actin driven process where the cell membrane folds outward to engulf surrounding fluid and particles into large vesicles inside the cell

Despite the pharmacokinetic limitations, irregular adsorption and fast catabolism, the l-dopa became the standard oral pharmaceutical therapy of PD in the last fifty years [7]

doi:10.1007/s00125-009-1499-0

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