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Description
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To date, effect of oral vitamin B12 treatment has not yet been adequately documented in patients presenting with severe neurological manifestations

Physiol., 255: F1122-F1127

Both offer energy benefits, but NAD+ improves how mitochondria work while B12 fixes low vitamin levels
Typical administration involves intramuscular or subcutaneous injection, with dosing individualized based on the severity of deficiency and clinical response

This protein binds to cobalamin with a high affinity and is encoded by a gene located on chromosome 22
