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These disruptions have been directly linked to the rapid rise in rates of type 2 diabetes, obesity, and cardiovascular diseases, which are now among the leading causes of mortality in the WHO South-East Asian region (Table 2)

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Nevertheless, appropriate tumor imaging at spatial resolution (e.g., use of PET radiotracers) may facilitate select effective metabolic therapy by determining what bioenergetic phenotype dominates in tumors (glycolytic, lipogenic, or oxidative) (121, 122)