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159 In addition, the DASH diet showed significant beneficial effects on cardiovascular risk

Thymosin beta 4 accelerates wound healing

and on day 30, before sacrifice

Importantly, creatine metabolism may also interact indirectly with gut microbial ecology and intestinal barrier function through shared amino acid pathways involving arginine and glycine metabolism, further supporting its inclusion within a broader hostmicrobiotametabolism framework (49, 50)

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23 Outcomes Outcomes were defined as: - Erythema migrans prevention, used as an unvalidated surrogate outcome for Lyme disease prevention measured after six weeks 12 , 18 , 22 24 - Any signs or symptoms of Lyme disease at any time within 30 days after intervention 20 - Adverse events after intervention within six weeks 23 or within 30 days